Mast cell activation syndrome is a condition that most doctors have never heard about, yet it is an important cause of illness that is underrecognized and, as a result, misdiagnosed. It belongs in the category of chronic inflammatory illnesses with symptoms including fatigue, allergy-like symptoms and problems with virtually every organ system in the body. Dr. Lawrence Afrin is a leading scientist and clinician on mast cell activation syndrome. Dr. Afrin is based out of the University of Minnesota and the author of the book Never Bet Against Occam, a book detailing his clinical experiences and knowledge of this mysterious disease.  

Dr. Jack Berger discusses his experiences as a medical consultant to the California Medical Board and a regular expert witness in cases in which doctors are accused of mis-prescribing opioids. Dr. Berger has served as the director of residency training in regional anesthesia and acute pain medicine since 2000 and holds the academic rank of Professor of Clinical Anesthesiology at the Keck School of Medicine of the University of Southern California. He has been practicing pain medicine since 1982.